cell reprogramming

Compared with the embryonic stem cell research, somatic cell reprogramming technology can supply pluripotent stem cells to more patients.

与胚胎干细胞研究相比，体细胞重编程技术可以为更多的患者提供特异性多能干细胞。

The researches of therapeutic cloning and somatic cell reprogramming, two strategies used to generate patient-specific autologous stem cells, have recently made great progress.

治疗性克隆和体细胞重编程是制备患者特异性自体干细胞的两种不同策略，近期已取得了重大的研究进展。

The medicine prize must, at some point, honour Shinya Yamanaka for cell reprogramming, though Britain's Sir Alec Jeffreys is in contention for DNA fingerprinting.

医学奖某些时候一定会因为细胞重新编程奖励Shinya Yamanaka，虽然英国爵士亚历克•杰弗里斯也在用DNA指纹竞争这一奖项。

Therapeutic Cloning and Somatic Cell Reprogramming: Every Road Leads to Rome

治疗性克隆与体细胞重编程：殊途同归

Recent researches found that cell fusion achieve effective reprogramming of cells function.

最近的研究表明细胞融合作为一种有效的再调控细胞功能的方法，得到广泛关注。

Except for somatic cell reprogramming developmental failure could cause abnormalities of cloned animals, the in vitro procedure and culture conditions also impact on development. And cause these abnormality have been appearanced mostly because all imprinted genes have been damaged, and could not be expressed normally.

而克隆动物除了本身供体细胞重编程的异常会导致发育失败，其体外操作过程和培养条件都会对发育造成影响，出现这些异常的主要原因就是印记基因表达调控受到影响而紊乱。

In addition, P53 gene is also linked inextricably with miRNA, human metabolism, somatic cell reprogramming and so on.

除此之外，P53基因与miRNA、人类的新陈代谢、体细胞的重编程等也都有着千丝万缕的联系。

IPSCs obtained from embryonic stem cells in the inner cell mass of blastocysts, the nuclear transfered embryonic stem cells and the exogenous transcription factor transferred somatic cells were used to conduct the somatic cell reprogramming research.

通常用来源于囊胚期胚胎的内细胞团的胚胎干细胞、通过核移植得到的胚胎干细胞以及在成体细胞中转入外源转录因子得到的iPSCs，进行体细胞重编程研究。

The new method also allows for genes that are inserted to trigger cell reprogramming to be removed afterwards.

新技术还可在成功诱导后去除触发细胞重编程的植入基因。

We are eager to explore the underlying transcriptional and epigenetic mechanisms of somatic cell reprogramming.

我们将研究在体细胞重编程过程中的转录调控和表观遗传调控机制。

Though it is merely a metaphor, the developmental landscape vividly describes the autonomous hierarchical bifurcation of cellular differentiation and implies the possibility of conversions between different cell types. Therefore, recently it is used extensively as a universal framework to explain both of the development and reprogramming.

虽然它只是一个隐喻，但其形象地描述了细胞的自发的层次分叉过程并隐含了细胞类型之间转换的可能性，从而作为一个整体框架最近被广泛应用来解释细胞发育和重编程。